InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CAPG

Summary

InnateDB Protein

IDBP-295391.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CAPG

Protein Name

capping protein (actin filament), gelsolin-like

Synonyms

AFCP; HEL-S-66; MCP;

Species

Homo sapiens

Ensembl Protein

ENSP00000387063

InnateDB Gene

IDBG-59043 (CAPG)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding

Biological Process

GO:0006461	protein complex assembly
GO:0051016	barbed-end actin filament capping

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0008290	F-actin capping protein complex
GO:0031965	nuclear membrane
GO:0042470	melanosome
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR007122 Villin/Gelsolin
IPR007123 Gelsolin-like domain

PFAM

PF00626

PRINTS

PR00597

PIRSF

SMART

SM00262

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P40121

PhosphoSite

PhosphoSite-P40121

TrEMBL

UniProt Splice Variant

Entrez Gene

822

UniGene

Hs.687978

RefSeq

NP_001243069

HUGO

HGNC:1474

OMIM

153615

CCDS

CCDS58715

HPRD

01088

IMGT

EMBL

AC062037 AK225374 BC000728 BC014549 CH471053 M94345 U12026

GenPept

AAA59570 AAA92670 AAH00728 AAH14549 AAY24128 EAW99517 EAW99518 EAW99519 EAW99520