InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ACTG2

Summary

InnateDB Protein

IDBP-295541.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ACTG2

Protein Name

actin, gamma 2, smooth muscle, enteric

Synonyms

ACT; ACTA3; ACTE; ACTL3; ACTSG; VSCM;

Species

Homo sapiens

Ensembl Protein

ENSP00000386857

InnateDB Gene

IDBG-56729 (ACTG2)

Protein Structure

UniProt Annotation

Function

Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.

Subcellular Localization

Cytoplasm, cytoskeleton.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	12 [view]
Protein-Protein	12 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005524	ATP binding

Biological Process

GO:0006936

muscle contraction

Cellular Component

GO:0005615	extracellular space
GO:0005829	cytosol
GO:0005856	cytoskeleton
GO:0071944	cell periphery
GO:0072562	blood microparticle

Protein Structure and Domains

PDB ID

InterPro

IPR004000 Actin-related protein

PFAM

PF00022

PRINTS

PR00190

PIRSF

SMART

SM00268

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P63267

PhosphoSite

PhosphoSite-P63267

TrEMBL

Q562S2

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

HUGO

HGNC:145

OMIM

102545

CCDS

CCDS1930

HPRD

00016

IMGT

EMBL

AC073046 AK304523 AK312955 AY970439 AY970440 BC012617 BC094877 CH471053 CR536515 CR541794 D00654 X16940

GenPept

AAH12617 AAH94877 AAX82248 AAX82249 AAX88909 BAA00546 BAG35794 BAG65327 CAA34814 CAG38753 CAG46593 EAW99713