InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: STK25

Summary

InnateDB Protein

IDBP-295547.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

STK25

Protein Name

serine/threonine kinase 25

Synonyms

SOK1; YSK1;

Species

Homo sapiens

Ensembl Protein

ENSP00000385541

InnateDB Gene

IDBG-85164 (STK25)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 49 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	49 [view]
Protein-Protein	49 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004713	protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0042803	protein homodimerization activity
GO:0046872	metal ion binding

Biological Process

GO:0006468	protein phosphorylation
GO:0006979	response to oxidative stress
GO:0007165	signal transduction
GO:0023014	signal transduction by phosphorylation
GO:0051645	Golgi localization

Cellular Component

GO:0005794

Golgi apparatus

Protein Structure and Domains

PDB ID

InterPro

IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR002290 Serine/threonine/dual specificity protein kinase, catalytic domain
IPR011009 Protein kinase-like domain
IPR020635 Tyrosine-protein kinase, catalytic domain

PFAM

PF00069
PF07714

PRINTS

PR00109

PIRSF

SMART

SM00220
SM00219

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt