InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ADCY7

Summary

InnateDB Protein

IDBP-30452.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ADCY7

Protein Name

adenylate cyclase 7

Synonyms

AC7;

Species

Homo sapiens

Ensembl Protein

ENSP00000254235

InnateDB Gene

IDBG-30450 (ADCY7)

Protein Structure

UniProt Annotation

Function

This is a membrane-bound, calcium-inhibitable adenylyl cyclase.

Subcellular Localization

Membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	4 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004016	adenylate cyclase activity
GO:0005524	ATP binding
GO:0016849	phosphorus-oxygen lyase activity
GO:0046872	metal ion binding

Biological Process

GO:0006112	energy reserve metabolic process
GO:0006833	water transport
GO:0007165	signal transduction
GO:0007173	epidermal growth factor receptor signaling pathway
GO:0007189	adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007202	activation of phospholipase C activity
GO:0007268	synaptic transmission
GO:0008543	fibroblast growth factor receptor signaling pathway
GO:0009190	cyclic nucleotide biosynthetic process
GO:0030819	positive regulation of cAMP biosynthetic process
GO:0034199	activation of protein kinase A activity
GO:0035556	intracellular signal transduction
GO:0044281	small molecule metabolic process
GO:0045087	innate immune response
GO:0048011	neurotrophin TRK receptor signaling pathway
GO:0055085	transmembrane transport
GO:0071361	cellular response to ethanol
GO:0071377	cellular response to glucagon stimulus