Version 5.4
Homo sapiens Protein: SNX20
Summary
InnateDB Protein IDBP-30622.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SNX20
Protein Name sorting nexin 20
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000300590
InnateDB Gene IDBG-30620 (SNX20)
Protein Structure
UniProt Annotation
Function Serves as a sorting protein that cycles P-selectin glycoprotein ligand 1 (PSLG1) into endosomes with no impact on leukocytes recruitment.
Subcellular Localization Cell membrane {ECO:0000269PubMed:18196517}. Cytoplasm {ECO:0000269PubMed:18196517}. Nucleus {ECO:0000269PubMed:18196517}. Endosome {ECO:0000269PubMed:18196517}. Endosome membrane {ECO:0000269PubMed:18196517}; Peripheral membrane protein {ECO:0000269PubMed:18196517}; Cytoplasmic side {ECO:0000269PubMed:18196517}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0035091 phosphatidylinositol binding
Biological Process
GO:0015031 protein transport
Cellular Component
GO:0005634 nucleus
GO:0005886 plasma membrane
GO:0010008 endosome membrane
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q7Z614
PhosphoSite PhosphoSite-Q7Z614
TrEMBL
UniProt Splice Variant
Entrez Gene 124460
UniGene Hs.715778
RefSeq NP_699168
HUGO HGNC:30390
OMIM 613281
CCDS CCDS10744
HPRD 15401
IMGT
EMBL AK292650 AK292705 AY302441 BC063423 BC119626 CH471092
GenPept AAH63423 AAI19627 AAP58362 BAF85339 BAF85394 EAW82763

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca