InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ADH6

Summary

InnateDB Protein

IDBP-31164.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ADH6

Protein Name

alcohol dehydrogenase 6 (class V)

Synonyms

ADH-5;

Species

Homo sapiens

Ensembl Protein

ENSP00000237653

InnateDB Gene

IDBG-31160 (ADH6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Cytoplasm.

Disease Associations

Tissue Specificity

Stomach and liver.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.

Experimentally validated
Total	11 [view]
Protein-Protein	8 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004022	alcohol dehydrogenase (NAD) activity
GO:0004024	alcohol dehydrogenase activity, zinc-dependent
GO:0008270	zinc ion binding
GO:0016491	oxidoreductase activity
GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
GO:0035276	ethanol binding

Biological Process

GO:0006069	ethanol oxidation
GO:0006805	xenobiotic metabolic process
GO:0044281	small molecule metabolic process
GO:0045471	response to ethanol
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005829	cytosol
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR011032 GroES (chaperonin 10)-like
IPR013149 Alcohol dehydrogenase, C-terminal
IPR013154 Alcohol dehydrogenase GroES-like
IPR020843 Polyketide synthase, enoylreductase

PFAM

PF00107
PF08240

PRINTS

PIRSF

SMART

SM00829

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P28332