Version 5.4
Homo sapiens Protein: CES5A
Summary
InnateDB Protein IDBP-31646.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CES5A
Protein Name carboxylesterase 5A
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000290567
InnateDB Gene IDBG-31642 (CES5A)
Protein Structure
UniProt Annotation
Function Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. {ECO:0000250}.
Subcellular Localization Secreted {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0016787 hydrolase activity
GO:0052689 carboxylic ester hydrolase activity
Biological Process
GO:0008152 metabolic process
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR002018 Carboxylesterase, type B
IPR013094 Alpha/beta hydrolase fold-3
IPR029058 Alpha/Beta hydrolase fold
PFAM PF00135
PF07859
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6NT32
PhosphoSite PhosphoSite-Q6NT32
TrEMBL I3NI11
UniProt Splice Variant
Entrez Gene 221223
UniGene Hs.350800
RefSeq NP_001137157
HUGO HGNC:26459
OMIM
CCDS CCDS45490
HPRD 07016
IMGT
EMBL AC007335 AC147362 AK056109 AK090997 AK294334 AY907669 BC069501 BC069548 BC117126 BC143692
GenPept AAH69501 AAH69548 AAI17127 AAI43693 AAX86044 BAB71094 BAC03565 BAH11738

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca