InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GDF7

Summary

InnateDB Protein

IDBP-32596.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GDF7

Protein Name

growth differentiation factor 7

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000272224

InnateDB Gene

IDBG-32594 (GDF7)

Protein Structure

UniProt Annotation

Function

May play an active role in the motor area of the primate neocortex. {ECO:0000250}.

Subcellular Localization

Secreted {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005125	cytokine activity
GO:0005515	protein binding
GO:0008083	growth factor activity
GO:0042803	protein homodimerization activity

Biological Process

GO:0007411	axon guidance
GO:0010628	positive regulation of gene expression
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0021509	roof plate formation
GO:0021527	spinal cord association neuron differentiation
GO:0021915	neural tube development
GO:0022612	gland morphogenesis
GO:0030509	BMP signaling pathway
GO:0030855	epithelial cell differentiation
GO:0030901	midbrain development
GO:0032924	activin receptor signaling pathway
GO:0040007	growth
GO:0045165	cell fate commitment
GO:0045666	positive regulation of neuron differentiation
GO:0045893	positive regulation of transcription, DNA-templated
GO:0048608	reproductive structure development
GO:0048754	branching morphogenesis of an epithelial tube
GO:0048853	forebrain morphogenesis
GO:0060389	pathway-restricted SMAD protein phosphorylation
GO:0060571	morphogenesis of an epithelial fold
GO:2001051	positive regulation of tendon cell differentiation