Version 5.4
Homo sapiens Protein: PITPNB
Summary
InnateDB Protein IDBP-3287.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PITPNB
Protein Name phosphatidylinositol transfer protein, beta
Synonyms PI-TP-beta; PtdInsTP; VIB1B;
Species Homo sapiens
Ensembl Protein ENSP00000321266
InnateDB Gene IDBG-3283 (PITPNB)
Protein Structure
UniProt Annotation
Function Catalyzes the transfer of PtdIns and phosphatidylcholine between membranes.
Subcellular Localization Cytoplasm {ECO:0000250}. Golgi apparatus {ECO:0000250}.
Disease Associations
Tissue Specificity Widely expressed in various tissues including brain.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 3 [view]
Protein-DNA 1 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008289 lipid binding
Biological Process
GO:0001701 in utero embryonic development
GO:0006629 lipid metabolic process
GO:0006644 phospholipid metabolic process
GO:0006810 transport
GO:0015914 phospholipid transport
GO:0044281 small molecule metabolic process
GO:0046474 glycerophospholipid biosynthetic process
Cellular Component
GO:0000139 Golgi membrane
GO:0005622 intracellular
GO:0005789 endoplasmic reticulum membrane
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR001666 Phosphatidylinositol transfer protein
PFAM PF02121
PRINTS PR00391
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P48739
PhosphoSite PhosphoSite-P48739
TrEMBL B3KYB6
UniProt Splice Variant
Entrez Gene 23760
UniGene Hs.7370
RefSeq NP_001271206
HUGO HGNC:9002
OMIM 606876
CCDS CCDS63433
HPRD 06044
IMGT
EMBL AK302367 AL031591 BC018704 BC031427 CH471095 CR456541 D30037
GenPept AAH18704 AAH31427 BAA06277 BAH13686 CAB63033 CAG30427 CAQ68296 EAW59743

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca