Version 5.4
Homo sapiens Protein: ELOVL6
Summary
InnateDB Protein IDBP-34176.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ELOVL6
Protein Name ELOVL fatty acid elongase 6
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000304736
InnateDB Gene IDBG-34174 (ELOVL6)
Protein Structure
UniProt Annotation
Function Condensing enzyme that catalyzes the synthesis of saturated and monounsaturated fatty acids. Highest activity toward C16:0 acyl-CoAs. {ECO:0000269PubMed:20937905}.
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000269PubMed:20937905}; Multi-pass membrane protein {ECO:0000269PubMed:20937905}.
Disease Associations
Tissue Specificity Ubiquitous. {ECO:0000269PubMed:20937905}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0019367 fatty acid elongation, saturated fatty acid
GO:0019432 triglyceride biosynthetic process
GO:0035338 long-chain fatty-acyl-CoA biosynthetic process
GO:0042759 long-chain fatty acid biosynthetic process
GO:0044255 cellular lipid metabolic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR002076 GNS1/SUR4 membrane protein
PFAM PF01151
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H5J4
PhosphoSite PhosphoSite-Q9H5J4
TrEMBL D6RHI2
UniProt Splice Variant
Entrez Gene 79071
UniGene Hs.652828
RefSeq NP_076995
HUGO HGNC:15829
OMIM 611546
CCDS CCDS3690
HPRD 13269
IMGT
EMBL AC004050 AC093770 AK027031 AK074813 BC001305 CH471057
GenPept AAH01305 AAY40928 BAB15632 BAC11225 EAX06259 EAX06260

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca