Homo sapiens Gene: ELOVL6
Summary
InnateDB Gene IDBG-34174.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ELOVL6
Gene Name ELOVL fatty acid elongase 6
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000170522
Encoded Proteins
ELOVL fatty acid elongase 6
ELOVL fatty acid elongase 6
ELOVL fatty acid elongase 6
ELOVL fatty acid elongase 6
ELOVL fatty acid elongase 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Fatty acid elongases (EC 6.2.1.3), such as ELOVL6, use malonyl-CoA as a 2-carbon donor in the first and rate-limiting step of fatty acid elongation (Moon et al., 2001 [PubMed 11567032]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:110045846-110199199
Strand Reverse strand
Band q25
Transcripts
ENST00000302274 ENSP00000304736
ENST00000394607 ENSP00000378105
ENST00000514184 ENSP00000424023
ENST00000507451
ENST00000506625 ENSP00000425488
ENST00000506461
ENST00000503885 ENSP00000426086
ENST00000513003
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0016740 transferase activity
GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups
Biological Process
GO:0006633 fatty acid biosynthetic process
GO:0019367 fatty acid elongation, saturated fatty acid
GO:0019432 triglyceride biosynthetic process
GO:0030497 fatty acid elongation
GO:0035338 long-chain fatty-acyl-CoA biosynthetic process
GO:0042759 long-chain fatty acid biosynthetic process
GO:0044255 cellular lipid metabolic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
GO:0030176 integral component of endoplasmic reticulum membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
Activation of gene expression by SREBF (SREBP) pathway
Metabolism of lipids and lipoproteins pathway
Fatty Acyl-CoA Biosynthesis pathway
Triglyceride Biosynthesis pathway
Regulation of cholesterol biosynthesis by SREBP (SREBF) pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Metabolism pathway
Synthesis of very long-chain fatty acyl-CoAs pathway
KEGG
Fatty acid elongation pathway
Biosynthesis of unsaturated fatty acids pathway
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.17519 Hs.412939 Hs.652828
RefSeq NM_001130721 NM_024090
HUGO
OMIM
CCDS CCDS3690
HPRD 13269
IMGT
EMBL
GenPept
RNA Seq Atlas