InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: MLL5

Summary

InnateDB Protein

IDBP-34747.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MLL5

Protein Name

myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000257745

InnateDB Gene

IDBG-34737 (MLL5)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	13 [view]
Protein-Protein	11 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003713	transcription coactivator activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0019899	enzyme binding
GO:0042800	histone methyltransferase activity (H3-K4 specific)

Biological Process

GO:0002446	neutrophil mediated immunity
GO:0006306	DNA methylation
GO:0006351	transcription, DNA-templated
GO:0007050	cell cycle arrest
GO:0030218	erythrocyte differentiation
GO:0030854	positive regulation of granulocyte differentiation
GO:0042119	neutrophil activation
GO:0045893	positive regulation of transcription, DNA-templated
GO:0048384	retinoic acid receptor signaling pathway
GO:0051568	histone H3-K4 methylation
GO:0071300	cellular response to retinoic acid