InnateDB Protein
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IDBP-34909.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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BSN
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Protein Name
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bassoon (presynaptic cytomatrix protein)
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Synonyms
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ZNF231;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000296452
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InnateDB Gene
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IDBG-34907 (BSN)
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Protein Structure
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Function |
Is thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act through binding to ERC2/CAST1. Essential in regulated neurotransmitter release from a subset of brain glutamatergic synapses. Involved in the formation of the retinal photoreceptor ribbon synapses (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cytoplasm {ECO:0000250}. Cell junction, synapse, synaptosome {ECO:0000250}. Cytoplasm, cytoskeleton. Note=Localized to the active zone of presynaptic density. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Exclusively expressed in brain. {ECO:0000269PubMed:9806829}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
6
[view]
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Protein-Protein |
6
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR008899
Zinc finger, piccolo-type
IPR011011
Zinc finger, FYVE/PHD-type
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PFAM |
PF05715
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9UPA5
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PhosphoSite |
PhosphoSite-Q9UPA5
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
8927
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UniGene |
Hs.194684
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RefSeq |
NP_003449
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HUGO |
HGNC:1117
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OMIM |
604020
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CCDS |
CCDS2800
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HPRD |
04933
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IMGT |
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EMBL |
AB007894
AC099668
AC104452
AF052224
Y18448
Y18449
Y18450
Y18451
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GenPept |
AAC83555
BAA23707
CAA77176
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