Homo sapiens Gene: BSN
Summary
InnateDB Gene IDBG-34907.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BSN
Gene Name bassoon (presynaptic cytomatrix protein)
Synonyms ZNF231
Species Homo sapiens
Ensembl Gene ENSG00000164061
Encoded Proteins
bassoon (presynaptic cytomatrix protein)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Neurotransmitters are released from a specific site in the axon terminal called the active zone, which is composed of synaptic vesicles and a meshwork of cytoskeleton underlying the plasma membrane. The protein encoded by this gene is thought to be a scaffolding protein involved in organizing the presynaptic cytoskeleton. The gene is expressed primarily in neurons in the brain. A similar gene product in rodents is concentrated in the active zone of axon terminals and tightly associated with cytoskeletal structures, and is essential for regulating neurotransmitter release from a subset of synapses. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:49554489-49671545
Strand Forward strand
Band p21.31
Transcripts
ENST00000296452 ENSP00000296452
ENST00000467456
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0007268 synaptic transmission
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0030054 cell junction
GO:0030424 axon
GO:0030425 dendrite
GO:0044306 neuron projection terminus
GO:0045202 synapse
GO:0048786 presynaptic active zone
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.194684
RefSeq NM_003458 XM_006713380
HUGO
OMIM
CCDS CCDS2800
HPRD 04933
IMGT
EMBL
GenPept
RNA Seq Atlas