Homo sapiens Gene: BSN
Summary
InnateDB Gene IDBG-34907.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BSN
Gene Name bassoon (presynaptic cytomatrix protein)
Synonyms ZNF231;
Species Homo sapiens
Ensembl Gene ENSG00000164061
Encoded Proteins
bassoon (presynaptic cytomatrix protein)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Neurotransmitters are released from a specific site in the axon terminal called the active zone, which is composed of synaptic vesicles and a meshwork of cytoskeleton underlying the plasma membrane. The protein encoded by this gene is thought to be a scaffolding protein involved in organizing the presynaptic cytoskeleton. The gene is expressed primarily in neurons in the brain. A similar gene product in rodents is concentrated in the active zone of axon terminals and tightly associated with cytoskeletal structures, and is essential for regulating neurotransmitter release from a subset of synapses. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:49554489-49671545
Strand Forward strand
Band p21.31
Transcripts
ENST00000296452 ENSP00000296452
ENST00000467456
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0007268 synaptic transmission
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0030054 cell junction
GO:0030424 axon
GO:0030425 dendrite
GO:0044306 neuron projection terminus
GO:0045202 synapse
GO:0048786 presynaptic active zone
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Cross-References
SwissProt Q9UPA5
TrEMBL
UniProt Splice Variant
Entrez Gene 8927
UniGene Hs.194684
RefSeq NM_003458 XM_006713380
HUGO HGNC:1117
OMIM 604020
CCDS CCDS2800
HPRD 04933
IMGT
EMBL AB007894 AC099668 AC104452 AF052224 Y18448 Y18449 Y18450 Y18451
GenPept AAC83555 BAA23707 CAA77176
RNA Seq Atlas 8927