InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: MTSS1

Summary

InnateDB Protein

IDBP-35103.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MTSS1

Protein Name

metastasis suppressor 1

Synonyms

MIM; MIMA; MIMB;

Species

Homo sapiens

Ensembl Protein

ENSP00000322804

InnateDB Gene

IDBG-35101 (MTSS1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003779	actin binding
GO:0003785	actin monomer binding
GO:0005102	receptor binding
GO:0005515	protein binding
GO:0008093	cytoskeletal adaptor activity
GO:0017124	SH3 domain binding
GO:0042802	identical protein binding
GO:0051015	actin filament binding

Biological Process

GO:0001701	in utero embryonic development
GO:0006928	cellular component movement
GO:0007009	plasma membrane organization
GO:0007015	actin filament organization
GO:0007155	cell adhesion
GO:0007165	signal transduction
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
GO:0010960	magnesium ion homeostasis
GO:0030035	microspike assembly
GO:0030036	actin cytoskeleton organization
GO:0030041	actin filament polymerization
GO:0030282	bone mineralization
GO:0032233	positive regulation of actin filament bundle assembly
GO:0034334	adherens junction maintenance
GO:0046847	filopodium assembly
GO:0050680	negative regulation of epithelial cell proliferation
GO:0061333	renal tubule morphogenesis
GO:0071498	cellular response to fluid shear stress
GO:0072001	renal system development
GO:0072102	glomerulus morphogenesis
GO:0072160	nephron tubule epithelial cell differentiation
GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis