InnateDB Protein
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IDBP-35817.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SOAT2
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Protein Name
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sterol O-acyltransferase 2
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Synonyms
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ACACT2; ACAT2; ARGP2;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000301466
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InnateDB Gene
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IDBG-35815 (SOAT2)
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Protein Structure
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|
Function |
Plays a role in lipoprotein assembly and dietary cholesterol absorption. In addition to its acyltransferase activity, it may act as a ligase. May provide cholesteryl esters for lipoprotein secretion from hepatocytes and intestinal mucosa.
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Subcellular Localization |
Endoplasmic reticulum membrane; Multi-pass membrane protein.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
4
[view]
|
Protein-Protein |
2
[view]
|
Protein-DNA |
2
[view]
|
Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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|
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR004299
Membrane bound O-acyl transferase, MBOAT
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PFAM |
PF03062
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PRINTS |
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PIRSF |
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SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
O75908
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PhosphoSite |
PhosphoSite-O75908
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
8435
|
UniGene |
Hs.656544
|
RefSeq |
NP_003569
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HUGO |
HGNC:11178
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OMIM |
601311
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CCDS |
CCDS8847
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HPRD |
03202
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IMGT |
|
EMBL |
AF059203
AF099031
AF331502
AF331503
AF331504
AF331505
AF331506
AF331507
AF331508
AF331509
AF331510
AF331511
AF331512
AF331513
AF331514
AF331515
AF331516
AF332857
AF332858
BC096091
BC096092
|
GenPept |
AAC63998
AAC78335
AAH96091
AAH96092
AAK18275
AAK48829
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