InnateDB Protein
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IDBP-35985.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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HAUS8
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Protein Name
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HAUS augmin-like complex, subunit 8
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000253669
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InnateDB Gene
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IDBG-35983 (HAUS8)
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Protein Structure
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Function |
Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. {ECO:0000269PubMed:18362163, ECO:0000269PubMed:19369198, ECO:0000269PubMed:19427217}.
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Subcellular Localization |
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=During interphase, primarily cytoplasmic and associates with centrosomes and with the mitotic spindles, preferentially at the spindle pole vicinity. During anaphase and telophase, additionally associates with the spindle midzone and midbody, respectively.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
15
[view]
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Protein-Protein |
15
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9BT25
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PhosphoSite |
PhosphoSite-Q9BT25
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
93323
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UniGene |
Hs.404088
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RefSeq |
NP_219485
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HUGO |
HGNC:30532
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OMIM |
613434
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CCDS |
CCDS32948
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HPRD |
11318
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IMGT |
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EMBL |
AC020908
AK295994
AY211919
BC004398
BC010176
CH471106
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GenPept |
AAH04398
AAH10176
AAO65172
BAG58769
EAW84570
EAW84571
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