InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PDE6B

Summary

InnateDB Protein

IDBP-360614.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PDE6B

Protein Name

phosphodiesterase 6B, cGMP-specific, rod, beta

Synonyms

CSNB3; CSNBAD2; PDEB; rd1; RP40;

Species

Homo sapiens

Ensembl Protein

ENSP00000406334

InnateDB Gene

IDBG-5946 (PDE6B)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	1 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
GO:0005515	protein binding
GO:0046872	metal ion binding
GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity

Biological Process

GO:0007165	signal transduction
GO:0007601	visual perception
GO:0007603	phototransduction, visible light
GO:0008152	metabolic process
GO:0016056	rhodopsin mediated signaling pathway
GO:0022400	regulation of rhodopsin mediated signaling pathway
GO:0046037	GMP metabolic process
GO:0051480	cytosolic calcium ion homeostasis

Cellular Component

GO:0005886	plasma membrane
GO:0097381	photoreceptor disc membrane

Protein Structure and Domains

PDB ID

InterPro

IPR002073 3\'5\'-cyclic nucleotide phosphodiesterase, catalytic domain
IPR003018 GAF domain
IPR003607 HD/PDEase domain
IPR023088 3\'5\'-cyclic nucleotide phosphodiesterase
IPR029016 GAF domain-like

PFAM

PF00233
PF01590
PF13185
PF13492

PRINTS

PR00387

PIRSF

SMART

SM00065
SM00471

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt