Version 5.4
Homo sapiens Protein: CSF2RA
Summary
InnateDB Protein IDBP-360999.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CSF2RA
Protein Name colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
Synonyms CD116; CDw116; CSF2R; CSF2RAX; CSF2RAY; CSF2RX; CSF2RY; GM-CSF-R-alpha; GMCSFR; GMR; SMDP4;
Species Homo sapiens
Ensembl Protein ENSP00000397452
InnateDB Gene IDBG-39400 (CSF2RA)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated
Total 12 [view]
Protein-Protein 12 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004896 cytokine receptor activity
GO:0005515 protein binding
Biological Process
GO:0019221 cytokine-mediated signaling pathway
Cellular Component
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR003961 Fibronectin, type III
IPR015321 Interleukin-6 receptor alpha, binding
PFAM PF00041
PF01108
PF09240
PRINTS
PIRSF
SMART SM00060
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL J3JS73
UniProt Splice Variant
Entrez Gene 1438
UniGene Hs.520937
RefSeq
HUGO HGNC:2435
OMIM 425000
CCDS
HPRD 02381
IMGT
EMBL BX649553
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca