InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: IGFALS

Summary

InnateDB Protein

IDBP-363757.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

IGFALS

Protein Name

insulin-like growth factor binding protein, acid labile subunit

Synonyms

ACLSD; ALS;

Species

Homo sapiens

Ensembl Protein

ENSP00000416683

InnateDB Gene

IDBG-9328 (IGFALS)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005520	insulin-like growth factor binding

Biological Process

GO:0007155	cell adhesion
GO:0007165	signal transduction
GO:0044267	cellular protein metabolic process

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005634	nucleus
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR000372 Leucine-rich repeat-containing N-terminal
IPR000483 Cysteine-rich flanking region, C-terminal
IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype

PFAM

PF01462
PF01463
PF00560
PF13504
PF13855

PRINTS

PIRSF

SMART

SM00013
SM00082
SM00369

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P35858