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InnateDB Protein
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IDBP-365275.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CHGB
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Protein Name
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chromogranin B (secretogranin 1)
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Synonyms
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SCG1;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000416643
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InnateDB Gene
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IDBG-51827 (CHGB)
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Protein Structure
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| Function |
Secretogranin-1 is a neuroendocrine secretory granule protein, which may be the precursor for other biologically active peptides.
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| Subcellular Localization |
Secreted. Note=Neuroendocrine and endocrine secretory granules.
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| Disease Associations |
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| Tissue Specificity |
Expressed in the adrenal medulla, and in pheochromocytoma. Not expressed in liver. {ECO:0000269PubMed:3608978}.
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 40 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
| Experimentally validated |
| Total |
40
[view]
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| Protein-Protein |
40
[view]
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| Protein-DNA |
0
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| Protein-RNA |
0
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| DNA-DNA |
0
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| RNA-RNA |
0
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| DNA-RNA |
0
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| Predicted by orthology |
| Total |
1 [view]
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Molecular Function |
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| Biological Process |
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| Cellular Component |
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| PDB ID |
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| InterPro |
IPR001819
Chromogranin A/B
IPR001990
Chromogranin/secretogranin
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| PFAM |
PF01271
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| PRINTS |
PR00659
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| PIRSF |
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| SMART |
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| TIGRFAMs |
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| Modification |
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| SwissProt |
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| PhosphoSite |
PhosphoSite-P05060
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| TrEMBL |
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| UniProt Splice Variant |
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| Entrez Gene |
1114
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| UniGene |
Hs.629339
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| RefSeq |
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| HUGO |
HGNC:1930
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| OMIM |
118920
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| CCDS |
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| HPRD |
07512
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| IMGT |
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| EMBL |
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| GenPept |
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Version 5.4