Version 5.4
Homo sapiens Gene: CHGB
Summary
InnateDB Gene IDBG-51827.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CHGB
Gene Name chromogranin B (secretogranin 1)
Synonyms SCG1
Species Homo sapiens
Ensembl Gene ENSG00000089199
Encoded Proteins
IDBP-51829
chromogranin B (secretogranin 1)
IDBP-365275
chromogranin B (secretogranin 1)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a tyrosine-sulfated secretory protein abundant in peptidergic endocrine cells and neurons. This protein may serve as a precursor for regulatory peptides. [provided by RefSeq, Jan 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:5911430-5925361
Strand Forward strand
Band p12.3
Transcripts
ENST00000378961 ENSP00000368244
ENST00000455042 ENSP00000416643
ENST00000488832
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 40 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 40 [view]
Protein-Protein 40 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005179 hormone activity
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005576 extracellular region
GO:0030141 secretory granule
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000027350
View Gene Order
ENSBTAG00000011782
Not yet available
Cross-References
SwissProt P05060
TrEMBL
UniProt Splice Variant
Entrez Gene 1114
UniGene Hs.516874 Hs.629339
RefSeq NM_001819
HUGO HGNC:1930
OMIM 118920
CCDS CCDS13092
HPRD
IMGT
EMBL AB209712 AK289386 AL035461 BC000375 CH471133 CR456726 Y00064
GenPept AAH00375 BAD92949 BAF82075 CAA68271 CAB55272 CAC34360 CAG33007 EAX10410
RNA Seq Atlas 1114

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca