InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SLC2A4

Summary

InnateDB Protein

IDBP-365301.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLC2A4

Protein Name

solute carrier family 2 (facilitated glucose transporter), member 4

Synonyms

GLUT4;

Species

Homo sapiens

Ensembl Protein

ENSP00000396887

InnateDB Gene

IDBG-24140 (SLC2A4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 41 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	41 [view]
Protein-Protein	39 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005355	glucose transmembrane transporter activity
GO:0022857	transmembrane transporter activity
GO:0022891	substrate-specific transmembrane transporter activity

Biological Process

GO:0015758	glucose transport
GO:0055085	transmembrane transport

Cellular Component

GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR002441 Glucose transporter, type 4 (GLUT4)
IPR003663 Sugar/inositol transporter
IPR005828 General substrate transporter
IPR011701 Major facilitator superfamily
IPR016196 Major facilitator superfamily domain, general substrate transporter
IPR020846 Major facilitator superfamily domain

PFAM

PF00083
PF07690

PRINTS

PR01193
PR00171

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite