Version 5.4
Homo sapiens Protein: CAD
Summary
InnateDB Protein IDBP-369005.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CAD
Protein Name carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000405416
InnateDB Gene IDBG-37744 (CAD)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 58 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 58 [view]
Protein-Protein 54 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016597 amino acid binding
GO:0016743 carboxyl- or carbamoyltransferase activity
Biological Process
GO:0006520 cellular amino acid metabolic process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR002082 Aspartate carbamoyltransferase
IPR006130 Aspartate/ornithine carbamoyltransferase
IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain
IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding
PFAM PF00185
PF02729
PRINTS PR00101
PR00100
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 790
UniGene Hs.377010
RefSeq
HUGO HGNC:1424
OMIM 114010
CCDS
HPRD 06437
IMGT
EMBL
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca