InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TIMP1

Summary

InnateDB Protein

IDBP-369458.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TIMP1

Protein Name

TIMP metallopeptidase inhibitor 1

Synonyms

CLGI; EPA; EPO; HCI; TIMP;

Species

Homo sapiens

Ensembl Protein

ENSP00000406671

InnateDB Gene

IDBG-61666 (TIMP1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.

Experimentally validated
Total	17 [view]
Protein-Protein	15 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008191	metalloendopeptidase inhibitor activity

Biological Process

GO:0010951

negative regulation of endopeptidase activity

Cellular Component

GO:0005576

extracellular region

Protein Structure and Domains

PDB ID

InterPro

IPR001134 Netrin domain
IPR001820 Proteinase inhibitor I35, tissue inhibitor of metalloproteinase
IPR008993 Tissue inhibitor of metalloproteinases-like, OB-fold

PFAM

PF00965

PRINTS

PIRSF

SMART

SM00206

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q5H9B5

UniProt Splice Variant

Entrez Gene

7076

UniGene

RefSeq

XP_005272702

HUGO

HGNC:11820

OMIM

305370

CCDS

HPRD

02371

IMGT

EMBL

Z84466

GenPept