Version 5.4
Homo sapiens Protein: GTF2H4
Summary
InnateDB Protein IDBP-370045.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GTF2H4
Protein Name general transcription factor IIH, polypeptide 4, 52kDa
Synonyms P52; TFB2; TFIIH;
Species Homo sapiens
Ensembl Protein ENSP00000410160
InnateDB Gene IDBG-237742 (GTF2H4)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 39 experimentally validated interaction(s) in this database.
Experimentally validated
Total 39 [view]
Protein-Protein 34 [view]
Protein-DNA 4 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004003 ATP-dependent DNA helicase activity
Biological Process
GO:0006289 nucleotide-excision repair
GO:0032508 DNA duplex unwinding
Cellular Component
GO:0000439 core TFIIH complex
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR004598 Transcription factor TFIIH subunit p52/Tfb2
PFAM PF03849
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL A2ABL5
UniProt Splice Variant
Entrez Gene 2968
UniGene Hs.485070
RefSeq
HUGO HGNC:4658
OMIM 601760
CCDS
HPRD 03456
IMGT
EMBL AL662870 AL669830
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca