Version 5.4
Homo sapiens Protein: NUDT6
Summary
InnateDB Protein IDBP-37113.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NUDT6
Protein Name nudix (nucleoside diphosphate linked moiety X)-type motif 6
Synonyms ASFGF2; FGF-AS; FGF2AS; GFG-1; GFG1;
Species Homo sapiens
Ensembl Protein ENSP00000306070
InnateDB Gene IDBG-37109 (NUDT6)
Protein Structure
UniProt Annotation
Function May contribute to the regulation of cell proliferation. {ECO:0000269PubMed:11266510}.
Subcellular Localization Cytoplasm. Nucleus. Mitochondrion. Note=Subcellular location may vary between isoforms.
Disease Associations
Tissue Specificity Detected in liver, kidney and esophagus (at protein level). Ubiquitous. {ECO:0000269PubMed:11266510, ECO:0000269PubMed:17569023}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 2 [view]
Protein-DNA 6 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008083 growth factor activity
GO:0016787 hydrolase activity
Biological Process
GO:0008150 biological_process
GO:0008152 metabolic process
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
GO:0005739 mitochondrion
Protein Structure and Domains
PDB ID
InterPro IPR000086 NUDIX hydrolase domain
IPR003293 Nudix hydrolase 6-like
IPR015797 NUDIX hydrolase domain-like
PFAM PF00293
PRINTS PR01356
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P53370
PhosphoSite PhosphoSite-P53370
TrEMBL
UniProt Splice Variant
Entrez Gene 11162
UniGene
RefSeq NP_009014
HUGO HGNC:8053
OMIM 606261
CCDS CCDS43268
HPRD 05880
IMGT
EMBL AF019632 AF019633 AK291871 BC009842 L31408
GenPept AAA67062 AAD01635 AAD01636 AAH09842 BAF84560

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca