InnateDB Protein
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IDBP-374377.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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DSN1
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Protein Name
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DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000389810
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InnateDB Gene
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IDBG-73404 (DSN1)
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Protein Structure
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Function |
Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. {ECO:0000269PubMed:15502821, ECO:0000269PubMed:16585270}.
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Subcellular Localization |
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with the kinetochore.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 37 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
37
[view]
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Protein-Protein |
36
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR013218
Kinetochore-associated protein Dsn1/Mis13
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PFAM |
PF08202
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9H410
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PhosphoSite |
PhosphoSite-Q9H410
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TrEMBL |
Q5JW57
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UniProt Splice Variant |
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Entrez Gene |
79980
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UniGene |
Hs.632268
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RefSeq |
NP_079194
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HUGO |
HGNC:16165
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OMIM |
609175
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CCDS |
CCDS13286
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HPRD |
16455
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IMGT |
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EMBL |
AK023408
AK093031
AK301671
AK301840
AL132768
BC058899
CH471077
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GenPept |
AAH58899
BAB14564
BAC04024
BAG63144
BAG63283
CAC10099
CAI21468
EAW76101
EAW76102
EAW76104
EAW76106
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