Homo sapiens Protein: IL2RG
Summary
InnateDB Protein IDBP-375001.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IL2RG
Protein Name interleukin 2 receptor, gamma
Synonyms CD132; CIDX; IL-2RG; IMD4; P64; SCIDX; SCIDX1;
Species Homo sapiens
Ensembl Protein ENSP00000388967
InnateDB Gene IDBG-74884 (IL2RG)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 32 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 32 [view]
Protein-Protein 32 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004911 interleukin-2 receptor activity
GO:0004913 interleukin-4 receptor activity
GO:0004917 interleukin-7 receptor activity
GO:0005515 protein binding
GO:0019976 interleukin-2 binding
Biological Process
GO:0006955 immune response
GO:0007165 signal transduction
GO:0016032 viral process
GO:0035771 interleukin-4-mediated signaling pathway
GO:0038110 interleukin-2-mediated signaling pathway
GO:0038111 interleukin-7-mediated signaling pathway
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0009897 external side of plasma membrane
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR003961 Fibronectin, type III
PFAM PF00041
PF01108
PRINTS
PIRSF
SMART SM00060
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P31785
PhosphoSite PhosphoSite-P31785
TrEMBL
UniProt Splice Variant
Entrez Gene 3561
UniGene
RefSeq
HUGO HGNC:6010
OMIM 308380
CCDS
HPRD 02391
IMGT
EMBL AB102794 AL590764 AY692262 BC014972 D11086 L12176 L12177 L12178 L12179 L12180 L12181 L12182 L12183 L19546
GenPept AAA59145 AAC37524 AAH14972 AAT85803 BAA01857 BAD89385