InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: UPP1

Summary

InnateDB Protein

IDBP-375033.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

UPP1

Protein Name

uridine phosphorylase 1

Synonyms

UDRPASE; UP; UPASE; UPP;

Species

Homo sapiens

Ensembl Protein

ENSP00000413611

InnateDB Gene

IDBG-16202 (UPP1)

Protein Structure

UniProt Annotation

Function

Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.

Experimentally validated
Total	10 [view]
Protein-Protein	10 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004850	uridine phosphorylase activity

Biological Process

GO:0006139	nucleobase-containing compound metabolic process
GO:0006206	pyrimidine nucleobase metabolic process
GO:0009166	nucleotide catabolic process
GO:0043097	pyrimidine nucleoside salvage
GO:0044206	UMP salvage
GO:0044281	small molecule metabolic process
GO:0046135	pyrimidine nucleoside catabolic process
GO:0055086	nucleobase-containing small molecule metabolic process