InnateDB Protein
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IDBP-375365.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CSPG5
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Protein Name
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chondroitin sulfate proteoglycan 5 (neuroglycan C)
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Synonyms
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NGC;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000392096
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InnateDB Gene
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IDBG-31813 (CSPG5)
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Protein Structure
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Function |
May function as a growth and differentiation factor involved in neuritogenesis. May induce ERBB3 activation. {ECO:0000269PubMed:15358134}.
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Subcellular Localization |
Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Golgi apparatus membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Note=In neurons, localizes to synaptic junctions. Also detected in the endoplasmic reticulum and the Golgi. Partially enriched in lipid rafts. {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
Restricted to brain (at protein level). {ECO:0000269PubMed:9950058}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
3
[view]
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Protein-Protein |
3
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR009505
Neural chondroitin sulphate proteoglycan cytoplasmic
IPR010555
Chondroitin sulphate attachment
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PFAM |
PF06567
PF06566
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
O95196
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PhosphoSite |
PhosphoSite-O95196
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
10675
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UniGene |
Hs.45127
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RefSeq |
NP_001193874
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HUGO |
HGNC:2467
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OMIM |
606775
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CCDS |
CCDS56252
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HPRD |
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IMGT |
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EMBL |
AC099778
AC112512
AF059274
AF461087
AF461088
AF461089
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GenPept |
AAC69612
AAQ04774
AAQ04775
AAQ04776
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