Version 5.4
Homo sapiens Protein: PFKFB4
Summary
InnateDB Protein IDBP-376122.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PFKFB4
Protein Name 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000393047
InnateDB Gene IDBG-32970 (PFKFB4)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 6 [view]
Protein-DNA 4 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003873 6-phosphofructo-2-kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006000 fructose metabolic process
GO:0006003 fructose 2,6-bisphosphate metabolic process
GO:0046835 carbohydrate phosphorylation
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR003094 Fructose-2,6-bisphosphatase
IPR013079 6-phosphofructo-2-kinase
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF01591
PRINTS PR00991
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL C9JX77
UniProt Splice Variant
Entrez Gene 5210
UniGene Hs.476217
RefSeq
HUGO HGNC:8875
OMIM 605320
CCDS
HPRD 05613
IMGT
EMBL AC134772
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca