Version 5.4
Homo sapiens Protein: XPO1
Summary
InnateDB Protein IDBP-377387.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol XPO1
Protein Name exportin 1 (CRM1 homolog, yeast)
Synonyms CRM1; emb; exp1;
Species Homo sapiens
Ensembl Protein ENSP00000408190
InnateDB Gene IDBG-53335 (XPO1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 204 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 204 [view]
Protein-Protein 202 [view]
Protein-DNA 1 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0008536 Ran GTPase binding
Biological Process
GO:0006886 intracellular protein transport
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001494 Importin-beta, N-terminal domain
IPR016024 Armadillo-type fold
PFAM PF03810
PRINTS
PIRSF
SMART SM00913
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL C9JQ02
UniProt Splice Variant
Entrez Gene 7514
UniGene Hs.717708
RefSeq
HUGO HGNC:12825
OMIM 602559
CCDS
HPRD 03975
IMGT
EMBL AC016727
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca