Version 5.4
Homo sapiens Protein: OTUD4
Summary
InnateDB Protein IDBP-378183.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OTUD4
Protein Name OTU domain containing 4
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000409279
InnateDB Gene IDBG-39849 (OTUD4)
Protein Structure
UniProt Annotation
Function Deubiquitinating enzyme that specifically hydrolyzes 'Lys-48'-linked polyubiquitin. {ECO:0000269PubMed:23827681}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 34 experimentally validated interaction(s) in this database.
Experimentally validated
Total 34 [view]
Protein-Protein 33 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004843 ubiquitin-specific protease activity
GO:0044822 poly(A) RNA binding
Biological Process
GO:0006508 proteolysis
GO:0071108 protein K48-linked deubiquitination
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID
InterPro IPR003323 Ovarian tumour, otubain
PFAM PF02338
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q01804
PhosphoSite PhosphoSite-Q01804
TrEMBL D6RA27
UniProt Splice Variant
Entrez Gene 54726
UniGene Hs.270851
RefSeq NP_001096123
HUGO HGNC:24949
OMIM 611744
CCDS CCDS47139
HPRD 11033
IMGT
EMBL AB028969 AC096757 AK056597 AK302581 AL137460 BC057242 BC118572 BC118653 CH471056 DQ427109 X68242
GenPept AAH57242 AAI18573 AAI18654 ABD72605 BAA82998 BAB71229 BAG63836 CAA48313 CAB70748 EAX05045 EAX05046

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca