Version 5.4
Homo sapiens Protein: HK1
Summary
InnateDB Protein IDBP-378239.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HK1
Protein Name hexokinase 1
Synonyms HK1-ta; HK1-tb; HK1-tc; HKD; HKI; HMSNR; HXK1;
Species Homo sapiens
Ensembl Protein ENSP00000415949
InnateDB Gene IDBG-76783 (HK1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 46 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 46 [view]
Protein-Protein 45 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004396 hexokinase activity
GO:0005524 ATP binding
GO:0016773 phosphotransferase activity, alcohol group as acceptor
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006096 glycolytic process
GO:0046835 carbohydrate phosphorylation
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001312 Hexokinase
IPR022672 Hexokinase, N-terminal
IPR022673 Hexokinase, C-terminal
PFAM PF00349
PF03727
PRINTS PR00475
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B1AR63
UniProt Splice Variant
Entrez Gene 3098
UniGene Hs.370365
RefSeq
HUGO HGNC:4922
OMIM 142600
CCDS
HPRD 00809
IMGT
EMBL AC016821 AL596223 AL672126
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca