Version 5.4
Homo sapiens Protein: BRF1
Summary
InnateDB Protein IDBP-378565.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BRF1
Protein Name BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae)
Synonyms BRF; BRF-1; GTF3B; hBRF; HEL-S-76p; TAF3B2; TAF3C; TAFIII90; TF3B90; TFIIIB90;
Species Homo sapiens
Ensembl Protein ENSP00000389859
InnateDB Gene IDBG-23236 (BRF1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
Experimentally validated
Total 20 [view]
Protein-Protein 20 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008270 zinc ion binding
GO:0017025 TBP-class protein binding
Biological Process
GO:0006352 DNA-templated transcription, initiation
GO:0006383 transcription from RNA polymerase III promoter
GO:0006384 transcription initiation from RNA polymerase III promoter
GO:0009303 rRNA transcription
GO:0009304 tRNA transcription
GO:0010467 gene expression
GO:0045893 positive regulation of transcription, DNA-templated
Cellular Component
GO:0000126 transcription factor TFIIIB complex
GO:0005634 nucleus
GO:0005654 nucleoplasm
Protein Structure and Domains
PDB ID
InterPro IPR011665 Brf1, TBP-binding domain
IPR013763 Cyclin-like
PFAM PF07741
PRINTS
PIRSF
SMART SM00385
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q92994
PhosphoSite PhosphoSite-Q92994
TrEMBL F8VQ19
UniProt Splice Variant
Entrez Gene 2972
UniGene Hs.666124
RefSeq NP_001229718
HUGO HGNC:11551
OMIM 604902
CCDS CCDS55949
HPRD 05361
IMGT
EMBL AJ297406 AJ297407 AJ297408 AK096471 AK124665 AK294899 AK295579 AL512355 BC016743 BC071637 BC086856 BC103859 CH471061 U28838 U75276
GenPept AAB38876 AAC50170 AAH16743 AAH71637 AAH86856 AAI03860 BAG53298 BAG54064 BAG58477 BAH11919 CAC04512 CAC04513 CAC04514 EAW81908 EAW81911

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca