Version 5.4
Homo sapiens Protein: ITIH3
Summary
InnateDB Protein IDBP-379732.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ITIH3
Protein Name inter-alpha (globulin) inhibitor H3
Synonyms H3P;
Species Homo sapiens
Ensembl Protein ENSP00000413922
InnateDB Gene IDBG-39731 (ITIH3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 2 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004867 serine-type endopeptidase inhibitor activity
Biological Process
GO:0010951 negative regulation of endopeptidase activity
GO:0030212 hyaluronan metabolic process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR002035 von Willebrand factor, type A
IPR010600 Inter-alpha-trypsin inhibitor heavy chain, C-terminal
IPR013694 VIT domain
PFAM PF00092
PF06668
PF08487
PF13757
PRINTS
PIRSF
SMART SM00327
SM00609
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E7ET33
UniProt Splice Variant
Entrez Gene 3699
UniGene Hs.76716
RefSeq
HUGO HGNC:6168
OMIM 146650
CCDS
HPRD 00891
IMGT
EMBL AC006254
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca