Version 5.4
Homo sapiens Protein: SEMA3E
Summary
InnateDB Protein IDBP-380560.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SEMA3E
Protein Name sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
Synonyms coll-5; M-SEMAH; M-SemaK; SEMAH;
Species Homo sapiens
Ensembl Protein ENSP00000405052
InnateDB Gene IDBG-24532 (SEMA3E)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
Biological Process
GO:0001569 patterning of blood vessels
GO:0001953 negative regulation of cell-matrix adhesion
GO:0002040 sprouting angiogenesis
GO:0007275 multicellular organismal development
GO:0007411 axon guidance
GO:0008360 regulation of cell shape
GO:0016525 negative regulation of angiogenesis
GO:0050808 synapse organization
GO:0071526 semaphorin-plexin signaling pathway
GO:2000249 regulation of actin cytoskeleton reorganization
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR001627 Sema domain
IPR007110 Immunoglobulin-like domain
IPR013106 Immunoglobulin V-set domain
IPR013151 Immunoglobulin
IPR016201 Plexin-like fold
PFAM PF01403
PF07686
PF00047
PRINTS
PIRSF
SMART SM00630
SM00423
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O15041
PhosphoSite PhosphoSite-O15041
TrEMBL C9JVH5
UniProt Splice Variant
Entrez Gene 9723
UniGene Hs.642416
RefSeq NP_001171600
HUGO HGNC:10727
OMIM 608166
CCDS CCDS55121
HPRD 11545
IMGT
EMBL AB002329 AC004954 AC006204 AC079799 AC079987 AK303925
GenPept AAC69513 AAS07487 AAS07488 BAA20789 BAG64853

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca