InnateDB Protein
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IDBP-381075.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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DCN
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Protein Name
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decorin
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Synonyms
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CSCD; DSPG2; PG40; PGII; PGS2; SLRR1B;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000398514
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InnateDB Gene
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IDBG-50872 (DCN)
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Protein Structure
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Function |
May affect the rate of fibrils formation.
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Subcellular Localization |
Secreted, extracellular space, extracellular matrix.
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Disease Associations |
Corneal dystrophy, congenital stromal (CSCD) [MIM:610048]: A corneal dystrophy characterized by congenital corneal opacification consisting of a large number of flakes and spots throughout all layers of the stroma. It results in progressive, painless visual loss. Corneal erosions and photophobia are absent. Note=The disease is caused by mutations affecting the gene represented in this entry.
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 25 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
25
[view]
|
Protein-Protein |
24
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR000372
Leucine-rich repeat-containing N-terminal
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PFAM |
PF01462
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PRINTS |
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PIRSF |
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SMART |
SM00013
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TIGRFAMs |
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Modification |
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SwissProt |
P07585
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PhosphoSite |
PhosphoSite-P07585
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
1634
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UniGene |
Hs.706674
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RefSeq |
NP_598014
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HUGO |
HGNC:2705
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OMIM |
125255
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CCDS |
CCDS44951
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HPRD |
00501
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IMGT |
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EMBL |
AF138300
AF138301
AF138302
AF138303
AF138304
AF491944
AH005442
BC005322
BT019800
L01125
L01126
L01127
L01129
L01130
L01131
M14219
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GenPept |
AAA52301
AAB00774
AAB60901
AAD44713
AAD44714
AAD44715
AAF61437
AAF61438
AAH05322
AAL92176
AAV38603
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