Version 5.4
Homo sapiens Protein: LIPA
Summary
InnateDB Protein IDBP-382106.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LIPA
Protein Name lipase A, lysosomal acid, cholesterol esterase
Synonyms CESD; LAL;
Species Homo sapiens
Ensembl Protein ENSP00000388415
InnateDB Gene IDBG-81838 (LIPA)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006629 lipid metabolic process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000073 Alpha/beta hydrolase fold-1
IPR006693 Partial AB-hydrolase lipase domain
IPR029058 Alpha/Beta hydrolase fold
PFAM PF00561
PF04083
PRINTS PR00111
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q5T770
UniProt Splice Variant
Entrez Gene 3988
UniGene Hs.741437
RefSeq
HUGO HGNC:6617
OMIM 613497
CCDS
HPRD 02044
IMGT
EMBL AL353146 AL353751 AL513533
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca