InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SAE1

Summary

InnateDB Protein

IDBP-382421.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SAE1

Protein Name

SUMO1 activating enzyme subunit 1

Synonyms

AOS1; HSPC140; SUA1; UBLE1A;

Species

Homo sapiens

Ensembl Protein

ENSP00000416557

InnateDB Gene

IDBG-59288 (SAE1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 56 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	56 [view]
Protein-Protein	56 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004839	ubiquitin activating enzyme activity
GO:0005515	protein binding
GO:0008022	protein C-terminus binding
GO:0008047	enzyme activator activity
GO:0019948	SUMO activating enzyme activity
GO:0043008	ATP-dependent protein binding
GO:0046982	protein heterodimerization activity

Biological Process

GO:0007346	regulation of mitotic cell cycle
GO:0008152	metabolic process
GO:0016567	protein ubiquitination
GO:0016925	protein sumoylation
GO:0019950	SMT3-dependent protein catabolic process
GO:0043085	positive regulation of catalytic activity
GO:0043687	post-translational protein modification
GO:0044267	cellular protein metabolic process