Homo sapiens Protein: MMP8
Summary
InnateDB Protein IDBP-382508.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MMP8
Protein Name matrix metallopeptidase 8 (neutrophil collagenase)
Synonyms CLG1; HNC; MMP-8; PMNL-CL;
Species Homo sapiens
Ensembl Protein ENSP00000401004
InnateDB Gene IDBG-69164 (MMP8)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 6 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004222 metalloendopeptidase activity
GO:0008237 metallopeptidase activity
GO:0008270 zinc ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0031012 extracellular matrix
Protein Structure and Domains
PDB ID
InterPro IPR000585 Hemopexin-like domain
IPR001818 Peptidase M10, metallopeptidase
IPR002477 Peptidoglycan binding-like
IPR006026 Peptidase, metallopeptidase
IPR018487 Hemopexin-like repeats
IPR021190 Peptidase M10A
PFAM PF00413
PF01471
PF00045
PRINTS PR00138
PIRSF
SMART SM00235
SM00120
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 4317
UniGene Hs.161839
RefSeq
HUGO HGNC:7175
OMIM 120355
CCDS
HPRD 00385
IMGT
EMBL
GenPept