InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: FBXO21

Summary

InnateDB Protein

IDBP-383822.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FBXO21

Protein Name

F-box protein 21

Synonyms

FBX21;

Species

Homo sapiens

Ensembl Protein

ENSP00000414468

InnateDB Gene

IDBG-59432 (FBXO21)

Protein Structure

UniProt Annotation

Function

Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.

Experimentally validated
Total	13 [view]
Protein-Protein	13 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0004842	ubiquitin-protein transferase activity

Biological Process

GO:0006511	ubiquitin-dependent protein catabolic process
GO:0016567	protein ubiquitination

Cellular Component

GO:0000151

ubiquitin ligase complex

Protein Structure and Domains

PDB ID

InterPro

IPR011722 Hemimethylated DNA-binding domain

PFAM

PF08755

PRINTS

PIRSF

SMART

SM00992

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

O94952

PhosphoSite

PhosphoSite-O94952

TrEMBL

Q4G104

UniProt Splice Variant

Entrez Gene

23014

UniGene

Hs.740376

RefSeq

HUGO

HGNC:13592

OMIM

609095

CCDS

HPRD

09948

IMGT

EMBL

AB020682 AC026364 AC026368 AF174601 AK001699 AL136899 BC034045 BC091496 CH471054

GenPept

AAF04522 AAH34045 AAH91496 BAA74898 BAG50962 CAB66833 EAW98105