Version 5.4
Homo sapiens Protein: ZEB2
Summary
InnateDB Protein IDBP-386307.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZEB2
Protein Name zinc finger E-box binding homeobox 2
Synonyms HSPC082; SIP-1; SIP1; SMADIP1; ZFHX1B;
Species Homo sapiens
Ensembl Protein ENSP00000395496
InnateDB Gene IDBG-71713 (ZEB2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 29 [view]
Protein-Protein 26 [view]
Protein-DNA 1 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 1 [view]
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001356 Homeobox domain
IPR007087 Zinc finger, C2H2
IPR009057 Homeodomain-like
IPR015880 Zinc finger, C2H2-like
PFAM PF00046
PF00096
PRINTS
PIRSF
SMART SM00389
SM00355
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL U3KPV5
UniProt Splice Variant
Entrez Gene 9839
UniGene Hs.739322
RefSeq
HUGO HGNC:14881
OMIM 605802
CCDS
HPRD 05780
IMGT
EMBL AC009951 AC010130
GenPept AAX93269

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca