InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: KNG1

Summary

InnateDB Protein

IDBP-386411.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

KNG1

Protein Name

kininogen 1

Synonyms

BDK; BK; KNG;

Species

Homo sapiens

Ensembl Protein

ENSP00000396025

InnateDB Gene

IDBG-69059 (KNG1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 22 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004869	cysteine-type endopeptidase inhibitor activity
GO:0005102	receptor binding
GO:0005515	protein binding
GO:0008201	heparin binding
GO:0008270	zinc ion binding

Biological Process

GO:0002576	platelet degranulation
GO:0006939	smooth muscle contraction
GO:0006954	inflammatory response
GO:0007162	negative regulation of cell adhesion
GO:0007204	positive regulation of cytosolic calcium ion concentration
GO:0007596	blood coagulation
GO:0007597	blood coagulation, intrinsic pathway
GO:0010951	negative regulation of endopeptidase activity
GO:0030168	platelet activation
GO:0030195	negative regulation of blood coagulation
GO:0035810	positive regulation of urine volume
GO:0035815	positive regulation of renal sodium excretion
GO:0042311	vasodilation
GO:0043065	positive regulation of apoptotic process
GO:0045861	negative regulation of proteolysis

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005886	plasma membrane
GO:0031093	platelet alpha granule lumen
GO:0070062	extracellular vesicular exosome
GO:0072562	blood microparticle