InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TP63

Summary

InnateDB Protein

IDBP-386579.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TP63

Protein Name

tumor protein p63

Synonyms

AIS; B(p51A); B(p51B); EEC3; KET; LMS; NBP; OFC8; p40; p51; p53CP; p63; p73H; p73L; RHS; SHFM4; TP53CP; TP53L; TP73L;

Species

Homo sapiens

Ensembl Protein

ENSP00000401661

InnateDB Gene

IDBG-69487 (TP63)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 159 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	159 [view]
Protein-Protein	138 [view]
Protein-DNA	17 [view]
Protein-RNA	0
DNA-DNA	3 [view]
RNA-RNA	1 [view]
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0044212	transcription regulatory region DNA binding

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0006915	apoptotic process
GO:0045087	innate immune response (InnateDB)

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR008967 p53-like transcription factor, DNA-binding
IPR011615 p53, DNA-binding domain

PFAM

PF00870

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

C9JW72

UniProt Splice Variant

Entrez Gene

8626

UniGene

Hs.137569

RefSeq

HUGO

HGNC:15979

OMIM

603273

CCDS

HPRD

04469

IMGT

EMBL

AC063939 AC078809 AC117486

GenPept