Version 5.4
Homo sapiens Protein: LMO7
Summary
InnateDB Protein IDBP-38678.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LMO7
Protein Name LIM domain 7
Synonyms FBX20; FBXO20; LOMP;
Species Homo sapiens
Ensembl Protein ENSP00000342112
InnateDB Gene IDBG-38674 (LMO7)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity Widely expressed. Isoform 2 and isoform 4 are predominantly expressed in brain. {ECO:0000269PubMed:11935316, ECO:0000269PubMed:9826547}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 26 [view]
Protein-Protein 25 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
GO:0016567 protein ubiquitination
Cellular Component
GO:0000151 ubiquitin ligase complex
GO:0005634 nucleus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR001478 PDZ domain
IPR001715 Calponin homology domain
IPR001781 Zinc finger, LIM-type
IPR003096 Smooth muscle protein/calponin
PFAM PF00595
PF13180
PF00307
PF00412
PRINTS PR00888
PIRSF
SMART SM00228
SM00033
SM00132
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8WWI1
PhosphoSite PhosphoSite-Q8WWI1
TrEMBL E9PLU6
UniProt Splice Variant
Entrez Gene 4008
UniGene Hs.705567
RefSeq NP_005349
HUGO HGNC:6646
OMIM 604362
CCDS CCDS9454
HPRD 05078
IMGT
EMBL AB020665 AF092554 AF092555 AF092556 AF092557 AF144237 AF174600 AF330045 AL137121 AL137244 AL137782 AL359392 U90654
GenPept AAB86592 AAC96299 AAC96300 AAD33924 AAF04521 AAL37480 BAA74881 CAI12422 CAI39480 CAI40007 CAI40209

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca