InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: LRP2

Summary

InnateDB Protein

IDBP-387336.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

LRP2

Protein Name

low density lipoprotein receptor-related protein 2

Synonyms

DBS; GP330;

Species

Homo sapiens

Ensembl Protein

ENSP00000409813

InnateDB Gene

IDBG-74420 (LRP2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 47 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	47 [view]
Protein-Protein	46 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005515	protein binding

Biological Process

Cellular Component

GO:0016021

integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000033 LDLR class B repeat
IPR000742 Epidermal growth factor-like domain
IPR001881 EGF-like calcium-binding domain
IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
IPR002919 Trypsin Inhibitor-like, cysteine rich domain

PFAM

PF00058
PF00008
PF07645
PF00057
PF01826

PRINTS

PR00261

PIRSF

SMART

SM00135
SM00181
SM00179
SM00192

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt