InnateDB Protein
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IDBP-388308.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CFLAR
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Protein Name
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CASP8 and FADD-like apoptosis regulator
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Synonyms
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c-FLIP; c-FLIPL; c-FLIPR; c-FLIPS; CASH; CASP8AP1; Casper; CLARP; FLAME; FLAME-1; FLAME1; FLIP; I-FLICE; MRIT;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000398551
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InnateDB Gene
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IDBG-78386 (CFLAR)
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Protein Structure
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Function |
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 66 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Experimentally validated |
Total |
66
[view]
|
Protein-Protein |
63
[view]
|
Protein-DNA |
2
[view]
|
Protein-RNA |
0
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DNA-DNA |
1
[view]
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RNA-RNA |
0
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DNA-RNA |
0
|
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Predicted by orthology |
Total |
8 [view]
|
|
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001875
Death effector domain
IPR011029
Death-like domain
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PFAM |
PF01335
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PRINTS |
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PIRSF |
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SMART |
SM00031
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TIGRFAMs |
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Modification |
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SwissProt |
|
PhosphoSite |
PhosphoSite-
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TrEMBL |
F8WBH9
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UniProt Splice Variant |
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Entrez Gene |
8837
|
UniGene |
Hs.609832
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RefSeq |
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HUGO |
HGNC:1876
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OMIM |
603599
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CCDS |
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HPRD |
04671
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IMGT |
|
EMBL |
AC007283
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GenPept |
|
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