InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: FDPS

Summary

InnateDB Protein

IDBP-388914.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FDPS

Protein Name

farnesyl diphosphate synthase

Synonyms

FPPS; FPS;

Species

Homo sapiens

Ensembl Protein

ENSP00000391755

InnateDB Gene

IDBG-103239 (FDPS)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.

Experimentally validated
Total	16 [view]
Protein-Protein	15 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004161	dimethylallyltranstransferase activity
GO:0004337	geranyltranstransferase activity
GO:0044822	poly(A) RNA binding
GO:0046872	metal ion binding

Biological Process

GO:0006695	cholesterol biosynthetic process
GO:0008299	isoprenoid biosynthetic process
GO:0016032	viral process
GO:0033384	geranyl diphosphate biosynthetic process
GO:0044281	small molecule metabolic process
GO:0045337	farnesyl diphosphate biosynthetic process

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol

Protein Structure and Domains

PDB ID

InterPro

IPR000092 Polyprenyl synthetase
IPR008949 Terpenoid synthase

PFAM

PF00348

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-P14324

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AK291084 AL139410 BC010004 BQ062616 CH471121 D14697 J05262 M29863

GenPept

AAA35820 AAA52423 AAH10004 BAA03523 BAF83773 CAI12715 EAW53076 EAW53077 EAW53078

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1)

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca